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imr90 human lung fibroblasts  (ATCC)


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    ATCC imr90 human lung fibroblasts
    Imr90 Human Lung Fibroblasts, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 2168 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+imr90+lung+fibroblasts/IMR-90/pm42209493-241-0-4
    Average 99 stars, based on 2168 article reviews
    imr90 human lung fibroblasts - by Bioz Stars, 2026-09
    99/100 stars

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    Cell Culture:

    Article Title: Development of novel flavonoid senolytics through phenotypic drug screening and drug design
    Article Snippet: .. Human IMR90 lung fibroblasts were obtained from American Type Culture Collection (ATCC) and cultured in EMEM medium with 10% FBS and pen/strep antibiotics. ..

    Article Title: Fibrates as drugs with senolytic and autophagic activity for osteoarthritis therapy
    Article Snippet: .. Human IMR90 lung fibroblasts were obtained from American Type Culture Collection (ATCC®, Cat# CCL-186, RRID:CVCL 0347) and cultured in EMEM medium with 10% FBS, 1% P/S antibiotics and 1% Glutamax. ..

    Article Title: Fucoidans are senotherapeutics that enhance SIRT6-dependent DNA repair
    Article Snippet: .. Human IMR90 lung fibroblasts were obtained from American Type Culture Collection (ATCC) and cultured in EMEM medium with 10% FBS and pen/strep antibiotics. ..

    Article Title: Identification of lipid senolytics targeting senescent cells through ferroptosis induction
    Article Snippet: .. Human IMR90 lung fibroblasts were obtained from American Type Culture Collection (ATCC) and cultured in EMEM medium with 10% FBS and pen/strep antibiotics. ..

    Article Title: Novel small molecule inhibition of IKK/NF‐κB activation reduces markers of senescence and improves healthspan in mouse models of aging
    Article Snippet: .. Human IMR90 lung fibroblasts were obtained from American Type Culture Collection (ATCC) and cultured in EMEM medium with 10% FBS and pen/strep antibiotics. ..

    Article Title: Identification of HSP90 inhibitors as a novel class of senolytics.
    Article Snippet: .. Human IMR90 lung fibroblasts were obtained from American Type Culture Collection (ATCC) and cultured in EMEM medium with 10% FBS and pen/strep antibiotics. ..

    Article Title: Polyunsaturated lipid senolytics exploit a ferroptotic vulnerability in senescent cells
    Article Snippet: .. Human IMR90 lung fibroblasts were obtained from American Type Culture Collection (ATCC) and cultured in EMEM medium with 10% FBS and pen/strep antibiotics. ..



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    human lung fibroblasts imr90  (ATCC)
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    (A) Viability of human <t>IMR90</t> cells after treatment with different doses of ENU. Proliferating cells were treated with ENU doses ranging from 25–500 μg/ml and the number of viable cells was assessed 72 hrs after treatment as a percentage of the control population (1-way ANOVA, R 2 = 0.9747); (B) Percentage of cells in early (Annexin positive) and late stage (7-AAD) apoptosis; (C) Viability of ENU-treated cells when confluent; (D) SNV frequency in human IMR90 cells after treatment with 20 or 100 μg/ml (1-way ANOVA, R 2 = 0.9259). IMR90: Institute for Medical Research-90; ENU: N-ethyl-N-nitrosourea; ANOVA: analysis of variance; 7-AAD: 7-aminoactinomycin D; SNV: single nucleotide variant.
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    (A) Viability of human IMR90 cells after treatment with different doses of ENU. Proliferating cells were treated with ENU doses ranging from 25–500 μg/ml and the number of viable cells was assessed 72 hrs after treatment as a percentage of the control population (1-way ANOVA, R 2 = 0.9747); (B) Percentage of cells in early (Annexin positive) and late stage (7-AAD) apoptosis; (C) Viability of ENU-treated cells when confluent; (D) SNV frequency in human IMR90 cells after treatment with 20 or 100 μg/ml (1-way ANOVA, R 2 = 0.9259). IMR90: Institute for Medical Research-90; ENU: N-ethyl-N-nitrosourea; ANOVA: analysis of variance; 7-AAD: 7-aminoactinomycin D; SNV: single nucleotide variant.

    Journal: Geromedicine

    Article Title: Mutagen-induced somatic mutation rate in primary mammalian cells in relation to maximum life span

    doi: 10.70401/geromedicine.2026.0023

    Figure Lengend Snippet: (A) Viability of human IMR90 cells after treatment with different doses of ENU. Proliferating cells were treated with ENU doses ranging from 25–500 μg/ml and the number of viable cells was assessed 72 hrs after treatment as a percentage of the control population (1-way ANOVA, R 2 = 0.9747); (B) Percentage of cells in early (Annexin positive) and late stage (7-AAD) apoptosis; (C) Viability of ENU-treated cells when confluent; (D) SNV frequency in human IMR90 cells after treatment with 20 or 100 μg/ml (1-way ANOVA, R 2 = 0.9259). IMR90: Institute for Medical Research-90; ENU: N-ethyl-N-nitrosourea; ANOVA: analysis of variance; 7-AAD: 7-aminoactinomycin D; SNV: single nucleotide variant.

    Article Snippet: Commercially available human lung fibroblasts (IMR90) were obtained via ATCC (CCL-186).

    Techniques: Control, Variant Assay