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imr90 human lung fibroblasts  (ATCC)


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    Structured Review

    ATCC imr90 human lung fibroblasts
    Imr90 Human Lung Fibroblasts, supplied by ATCC, used in various techniques. Bioz Stars score: 99/100, based on 2160 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/product/human+imr90+lung+fibroblasts/pm42209493-241-0-4?v=ATCC
    Average 99 stars, based on 2160 article reviews
    imr90 human lung fibroblasts - by Bioz Stars, 2026-08
    99/100 stars

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    ATCC human lung fibroblasts imr90
    (A) Viability of human <t>IMR90</t> cells after treatment with different doses of ENU. Proliferating cells were treated with ENU doses ranging from 25–500 μg/ml and the number of viable cells was assessed 72 hrs after treatment as a percentage of the control population (1-way ANOVA, R 2 = 0.9747); (B) Percentage of cells in early (Annexin positive) and late stage (7-AAD) apoptosis; (C) Viability of ENU-treated cells when confluent; (D) SNV frequency in human IMR90 cells after treatment with 20 or 100 μg/ml (1-way ANOVA, R 2 = 0.9259). IMR90: Institute for Medical Research-90; ENU: N-ethyl-N-nitrosourea; ANOVA: analysis of variance; 7-AAD: 7-aminoactinomycin D; SNV: single nucleotide variant.
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    (A) Viability of human IMR90 cells after treatment with different doses of ENU. Proliferating cells were treated with ENU doses ranging from 25–500 μg/ml and the number of viable cells was assessed 72 hrs after treatment as a percentage of the control population (1-way ANOVA, R 2 = 0.9747); (B) Percentage of cells in early (Annexin positive) and late stage (7-AAD) apoptosis; (C) Viability of ENU-treated cells when confluent; (D) SNV frequency in human IMR90 cells after treatment with 20 or 100 μg/ml (1-way ANOVA, R 2 = 0.9259). IMR90: Institute for Medical Research-90; ENU: N-ethyl-N-nitrosourea; ANOVA: analysis of variance; 7-AAD: 7-aminoactinomycin D; SNV: single nucleotide variant.

    Journal: Geromedicine

    Article Title: Mutagen-induced somatic mutation rate in primary mammalian cells in relation to maximum life span

    doi: 10.70401/geromedicine.2026.0023

    Figure Lengend Snippet: (A) Viability of human IMR90 cells after treatment with different doses of ENU. Proliferating cells were treated with ENU doses ranging from 25–500 μg/ml and the number of viable cells was assessed 72 hrs after treatment as a percentage of the control population (1-way ANOVA, R 2 = 0.9747); (B) Percentage of cells in early (Annexin positive) and late stage (7-AAD) apoptosis; (C) Viability of ENU-treated cells when confluent; (D) SNV frequency in human IMR90 cells after treatment with 20 or 100 μg/ml (1-way ANOVA, R 2 = 0.9259). IMR90: Institute for Medical Research-90; ENU: N-ethyl-N-nitrosourea; ANOVA: analysis of variance; 7-AAD: 7-aminoactinomycin D; SNV: single nucleotide variant.

    Article Snippet: Commercially available human lung fibroblasts (IMR90) were obtained via ATCC (CCL-186).

    Techniques: Control, Variant Assay